从2011年开始，美国癌症学会每两年对美国女性乳腺癌统计学数据进行更新，其中包括发病率、死亡率、生存率和筛查率。
2019年10月2日，影响因子全球第一神刊、美国癌症学会《临床医师癌症杂志》在线发表美国癌症学会、康奈尔大学威尔医学中心的2019年度美国女性乳腺癌发病率、死亡率、生存率和筛查率统计学数据报告。
2018年度全球主要期刊影响因子
- 临床医师癌症杂志：223.679
- 新英格兰医学杂志：70.67
- 柳叶刀：59.102
- 自然综述癌症分册：51.848
- 美国医学会杂志：51.273
- 自然：43.07
- 科学：41.037
- 细胞：36.216
- 柳叶刀肿瘤学分册：35.386
最近5年（2012～2016年），乳腺癌发病率每年略微增加0.3%，主要由于局部乳腺癌和激素受体阳性乳腺癌的发病率增加。
相比之下，乳腺癌死亡率继续减少，由1989年至2017年减少40%，相当于减少了37万5900例乳腺癌死亡。
值得注意的是，乳腺癌死亡率每年减少速度已经由1998～2011年的1.9%放缓至2011～2017年的1.3%，主要由于白人女性乳腺癌死亡率每年减少速度放缓。因此，过去30年黑人与白人的乳腺癌死亡率差距有所扩大之后，2011年以来一直保持稳定。不过，黑人与白人相比，虽然发病率较低（十万分之126.7比130.8），但是死亡率仍然高40%（十万分之28.4比20.3）；年龄<50岁的黑人与白人相比，该差距增加，死亡率翻倍。
最近5年（2013～2017年），西班牙裔、黑人、白人、亚洲和太平洋岛民的死亡率减少（每年2.1%、1.5%、1.0%、0.8%），但是美洲印第安人和阿拉斯加土著人的死亡率稳定。不过，某些州的乳腺癌死亡率不再减少：内布拉斯加州的全部女性，科罗拉多州和威斯康辛州的黑人女性，内布拉斯加州、德克萨斯州和弗吉尼亚州的白人女性。2016～2017年，乳腺癌是南部四个州和中西部两个州黑人女性、犹他州白人女性的癌症死亡主要原因（超过肺癌）。
因此，该研究结果表明，通过扩大所有女性获得高质量预防、早期发现和治疗服务的机会，可以加快乳腺癌死亡率的减少。
CA Cancer J Clin. 2019 Oct 2. [Epub ahead of print]
Breast cancer statistics, 2019.
DeSantis CE, Ma J, Gaudet MM, Newman LA, Miller KD, Goding Sauer A, Jemal A, Siegel RL.
American Cancer Society, Atlanta, Georgia; Weill Cornell Medical Center, New York, New York.
This article is the American Cancer Society's biennial update on female breast cancer statistics in the United States, including data on incidence, mortality, survival, and screening. Over the most recent 5-year period (2012-2016), the breast cancer incidence rate increased slightly by 0.3% per year, largely because of rising rates of local stage and hormone receptor-positive disease. In contrast, the breast cancer death rate continues to decline, dropping 40% from 1989 to 2017 and translating to 375,900 breast cancer deaths averted. Notably, the pace of the decline has slowed from an annual decrease of 1.9% during 1998 through 2011 to 1.3% during 2011 through 2017, largely driven by the trend in white women. Consequently, the black-white disparity in breast cancer mortality has remained stable since 2011 after widening over the past 3 decades. Nevertheless, the death rate remains 40% higher in blacks (28.4 vs 20.3 deaths per 100,000) despite a lower incidence rate (126.7 vs 130.8); this disparity is magnified among black women aged <50 years, who have a death rate double that of whites. In the most recent 5-year period (2013-2017), the death rate declined in Hispanics (2.1% per year), blacks (1.5%), whites (1.0%), and Asians/Pacific Islanders (0.8%) but was stable in American Indians/Alaska Natives. However, by state, breast cancer mortality rates are no longer declining in Nebraska overall; in Colorado and Wisconsin in black women; and in Nebraska, Texas, and Virginia in white women. Breast cancer was the leading cause of cancer death in women (surpassing lung cancer) in four Southern and two Midwestern states among blacks and in Utah among whites during 2016-2017. Declines in breast cancer mortality could be accelerated by expanding access to high-quality prevention, early detection, and treatment services to all women.
KEYWORDS: breast neoplasms; epidemiology; health disparities; incidence; molecular subtype; mortality
PMID: 31577379
DOI: 10.3322/caac.21583
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